2017.11.08 / Wednesday
The Effect of Hypothermia on Coagulation Function
Perioperative hypothermia is one of the most frequently asked questions in body temperature management. There are many sequelae cause by hypothermia, among them, hypothermia on coagulation function is not trivial.
Mild hypothermia can reduce number of platelets in the blood circulation, reduce platelet function, reduce the activity of the clotting factors, and activate blood fibrinolysis system, which can lead to prolonged bleeding.
One point should be pay attention that severe hypothermia can lead to DIC.
In a clinical observation, the bleeding time was inversely proportional to the skin temperature, and amount of blood was inversely proportional to the temperature of the wound.
On the other hand, the hypothermia causes venous stasis and local tissue oxygenation, which further leads to the formation of deep vein thrombosis.