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The Role of Volumetric Dynamics Monitoring in Guiding Fluid Therapy

2019.08.16 / Friday

The Role of Volumetric Dynamics Monitoring in Guiding Fluid Therapy



As we all know, quantitative study of volume dynamics is a dynamic change law of distribution and elimination of body fluid volume under the influence of various factors in vivo and in vitro.
Normally, capacity dynamics is divided into static capacity dynamics model and dynamic capacity dynamics model.


The static volumetric dynamics model predicts the static effect of plasma volume expansion after intravenous infusion.

It can be expressed as plasma volume expansion = input volume × (plasma volume/fluid distribution volume).

However, fluid balance is a dynamic process, and both the static dynamic model and the frank-starling law assume that there is a fixed fluid gap in the body, so the static volumetry model has some disadvantages.


Due to the comprehensive influence of anesthetic factors, surgical factors and patients' own factors, the fluid gap volume of patients is constantly changing. Therefore, the researchers also proposed a dynamic model of plasma volume expansion, including the one-compartment model, two-compartment model and three-compartment model.

These models, like pharmacokinetics, are a virtual space where their equations can be derived based on assumptions.

One-compartment and two-compartment models are suitable for isotonic solutions, while three-compartment models are suitable for hypertonic or hypotonic liquids.


Anesthesiologists need to combine specific hemodynamic indicators with the patient's own condition, and use the medical temperature probe to monitor the patient's temperature in real time, develop a reasonable treatment plan, and then implement liquid therapy.


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